MIT neuroscience professor Pawan Sinha (Robin Lubbock/WBUR)
MIT neuroscience professor Pawan Sinha still gets goosebumps when he thinks about it, he says: “Things just happened so perfectly, so well-timed.”
Back in 2002, Sinha was grappling with a deep scientific question: How do we learn to recognize the objects we see? How do our brains know, “That’s a face”? Or “That’s a table”?
A fateful taxi ride set his research — and his life — onto a new road.
He was back visiting New Delhi, where he grew up on the elite campus of the Indian Institute of Technology before coming to America for graduate school. He was on his way to see a friend one evening, when the taxi he was riding in stopped at a traffic light.
“I noticed, by the side of the road was this little family, a mother and her two children,” he says. “And it felt really terrible to see these two children, who were barely wearing any clothes, very young children on this cold winter day. So I called over the mother to give her a little bit of change.”
When she approached, Sinha noticed that both of the children holding on to her sari had cataracts clouding their eyes.
It was the first time that he had seen children with cataracts. When he looked into childhood blindness in India, he learned that it is a widespread problem, often caused by rubella during the mother’s pregnancy. Blind children in the developing world suffer so much abuse and neglect that more than half don’t survive to age 5, he says.
Sinha wanted to help, but he figured that what he could contribute on his academic salary would be just a drop in the ocean.
“And that’s when the realization struck me that in providing treatment to those children, I would have exactly the approach that I had been looking for in my scientific work,” he says.
“If you have a child, say, a 10-year-old child who has not seen from birth, has only seen light and dark, and in a matter of half an hour you’re able to initiate sight in this child, then from the very next day, when the bandages are removed, you have a ringside seat into the process of visual development.”
Sinha applied for a federal grant to pay for cataract operations, which are relatively simple, and for studying the children who got them. Usually, American research money stays in America, “but I took a chance because I completely, honestly believed, and believe, that in providing that surgery, we are benefiting science that belongs to all of mankind, it’s not just specifically India.”
That grant eventually came though and to continue the work, Sinha founded a nonprofit based in New Delhi. He named it Project Prakash; Prakash means “light” in Sanskrit. Since 2005, he says, nearly 500 Indian children have gained sight through the project.
Now, at 48, Sinha is planning a major expansion of Project Prakash, to create a center that includes a hospital, a school and a research facility. The goal is to serve many more children than the current 40 to 50 a year. Continue reading