God help us, when will it ever stop? Is there no organ, no medical condition, no tiny part of the human body that is not helped by exercise?
A new mouse study in the The Journal of Neuroscience finds that exercise appears to be good for the retina, and may even slow the development of age-related macular degeneration, which is estimated to affect nearly 2 million older Americans. The key appears to be a helpful protein called brain-derived neurotrophic factor. From the press release:
Moderate aerobic exercise helps to preserve the structure and function of nerve cells in the retina after damage, according to an animal study appearing February 12 in The Journal of Neuroscience. The findings suggest exercise may be able to slow the progression of retinal degenerative diseases.
Age-related macular degeneration, one of the leading causes of blindness in the elderly, is caused by the death of light-sensing nerve cells in the retina called photoreceptors. Although several studies in animals and humans point to the protective effects of exercise in neurodegenerative diseases or injury, less is known about how exercise affects vision.
Machelle Pardue, PhD, together with her colleagues Eric Lawson and Jeffrey H. Boatright, PhD, at the Atlanta VA Center for Visual and Neurocognitive Rehabilitation and Emory University, ran mice on a treadmill for two weeks before and after exposing the animals to bright light that causes retinal degeneration. The researchers found that treadmill training preserved photoreceptors and retinal cell function in the mice.
“This is the first report of simple exercise having a direct effect on retinal health and vision,” Pardue said. “This research may one day lead to tailored exercise regimens or combination therapies in treatments of blinding diseases.” Continue reading